Sulfur-Doped Carbon Dots as a Highly Selective and Sensitive Fluorescent Probe for Copper Ion Detection in Biological Systems.

ABSTRACT: Copper ions are regarded as a double-edged sword since it plays a crucial role in biological functions but can also induce various severe diseases at imbalanced levels. However, conventional methods for quantifying copper ion (Cu²⁺) levels often encounter complicated preparation procedures and interference from other substances. This study describes the one-pot microwave synthesis of sulfur-doped carbon dot (S_HICA) as a highly selective and sensitive fluorescent probe for Cu²⁺ detection in biological systems. S_HICA demonstrates improved fluorescence properties such as increased intensity and a red-shifted emission wavelength compared to carbon dots without sulfur (HICA), and S_HICA exhibits outstanding selectivity for Cu²⁺ through a fluorescence quenching

SUBMITTER: Jin M 

PROVIDER: S-EPMC12632436 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature