Delirium is associated with incident dementia across the multimorbidity spectrum: a population-based cohort study.

ABSTRACT:

Background

Delirium is strongly associated with subsequent dementia, but this is often assumed to reflect underlying associations of baseline health with dementia. We examined the associations of delirium on admission with incident dementia across the spectrum of multimorbidity.

Methods

Retrospective population-based cohort study using linked primary care and hospital data for emergency admissions aged ≥65 years in Lothian, Scotland, from 1 Apr 2017 to 1 Apr 2020. Delirium on admission was assessed at the bedside for all patients using the 4AT (www.the4AT.com). Associations of delirium, multimorbidity, and their interaction with incident dementia and mortality were examined using Fine-Gray competing-risks regression and Cox proportional hazards models.

Results

Of 23,5

SUBMITTER: Penfold RS 

PROVIDER: S-EPMC12632668 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature