Neuromechanical gait signatures reveal holistic biomechanical responses to walking speed modulation in stroke survivors.

ABSTRACT: During gait rehabilitation, determining the walking speed that optimizes an individual's biomechanical gait quality is challenging because discrete biomechanical variables used to quantify gait quality change differentially with speed. We recently developed gait signatures that may provide a holistic representation of biomechanical gait quality by implicitly modeling the neuromechanical dynamics of walking. Here, we characterized speed-induced changes in post-stroke gait signatures and their relationship to 14 discrete biomechanical variables in 19 stroke survivors and 5 able-bodied adults walking at 6 speeds. With increasing speed, post-stroke gait signatures became more like able-bodied gait signatures, suggesting improved gait quality. Inter-individual differences in the directio

SUBMITTER: Rosenberg MC 

PROVIDER: S-EPMC12632674 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature