IDBac: an open-access web platform and compendium for the identification of bacteria by MALDI-TOF mass spectrometry.

ABSTRACT: The identification of bacteria is central to the microbiological sciences. While gene sequencing methods have been the standard to identify bacteria, use of MALDI-TOF mass spectrometry (MS) in clinical microbiology provides high-throughput identification to the subspecies level. However, biotyping has yet to be adopted outside of clinical settings due to the lack of a centralized public database of MS protein signatures that would facilitate strain identification via spectral comparison. Herein we present the IDBac web platform, a crowd-sourced central knowledgebase of protein MS signatures of >1400 strains spanning 6 bacterial phyla. Accompanying the knowledgebase is analysis infrastructure to identify unknown isolates, probe relationships within culture collections, and visualize special

SUBMITTER: Krull NK 

PROVIDER: S-EPMC12632805 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature