Synthesis of a nano-emulsion of quercetin encapsulated vitamin E conjugated iron oxide nanoparticles for the systemic phyto-preventive effect: characterization and oral cancer application.

ABSTRACT: Background: Globally, one of the most pressing public health concerns is the prevention of oral cancerous lesions. This study aimed to reverse the carcinogenic effect of DMBA in hamsters by using nano-emulsions of quercetin encapsulated vitamin E and iron oxide. Methods: The studied iron oxide nanoparticles were prepared by the co-precipitation method and then converted into nano-emulsions via the oil-in-water technique and characterized. The study included five equal groups of 30 Syrian male hamsters aged eight weeks. Group A constituted a negative control, and Group B received 25 mg kg^-1 of nano-emulsion orally three times per week for eight weeks. Group C (positive control) was painted with DMBA on the left pouches three times per week for six weeks. Grou

SUBMITTER: El-Mansy MN 

PROVIDER: S-EPMC12633408 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature