Dynamics of Dentate Gyrus Place Cells and Dentate Spikes Signal Spatial and Nonspatial Changes in Environments.

ABSTRACT: The dentate gyrus (DG) is thought to play a key role in the formation of dissociable memory representations for similar contexts. Neurons in the dentate gyrus (DG) receive highly processed spatial and nonspatial sensory information from the medial and lateral entorhinal cortices, respectively. Changes in spatially tuned firing patterns of DG place cells occur after spatial changes to an environment, but the degree to which DG place cells respond to ethologically relevant nonspatial stimuli is largely unknown. Spatial and nonspatial information is thought to be transmitted to the DG during discrete local field potential events called dentate spikes. Here, we tested the extent to which different spatial and nonspatial stimuli modulate place cell firing patterns and dentate spike dynamics. We

SUBMITTER: Demetrovich PG 

PROVIDER: S-EPMC12633412 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature