Quantifying intra-individual variability in anatomical sites of pain in longitudinal studies.

ABSTRACT: Longitudinal pain studies present an opportunity to understand intra-individual variations in pain. However, current methods to quantify the anatomical extent of pain fail to capture variations across multiple body sites over time. Our aims were to (1) describe patterns of intra-individual variation in pain sites over time, (2) develop a metric that quantifies intra-individual variation in pain sites over time, and (3) determine whether this metric is related to other indicators of pain burden. We used data from a longitudinal cohort of 72 participants (51 female; median (IQR) age 43 (37-51) years) living with virally suppressed HIV, who provided weekly reports of pain severity, pain site(s), and distress over 49 weeks. Participant reports showed noteworthy intra-individual changes in pain

SUBMITTER: Madden VJ 

PROVIDER: S-EPMC12633564 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature