Quantitative Analysis of Retinal Nerve Fiber Layer Thickness Using SPECTRALIS Glaucoma Module Premium Edition and SPECTRALIS Standard Glaucoma Module.

ABSTRACT:

Purpose

To evaluate the relationship between retinal nerve fiber layer (RNFL) thickness measured by SPECTRALIS Glaucoma Module Premium Edition (GMPE) and SPECTRALIS Standard Glaucoma Module (SGM).

Methods

This was a cross-sectional study of glaucoma and glaucoma suspect patients from an academic center between May and October 2023. Peripapillary RNFL thickness was measured using GMPE and SGM on the same day; only scans with good centration and reliable segmentation in both modalities were analyzed.

Results

Of 1277 eyes (665 patients) reviewed, 766 eyes (465 patients) met inclusion criteria. Global and sectoral RNFL thicknesses were highly correlated between GMPE and SGM (r ≥ 0.844; ICC ≥ 0.706; P < 0.001 for all); however, global and sectoral RNFL thicknesses between

SUBMITTER: Chen DX 

PROVIDER: S-EPMC12633779 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature