Prospective pooled analyses of ambient ultraviolet radiation levels and risk of non-Hodgkin lymphoma and multiple myeloma.

ABSTRACT: Case-control studies of sun exposure and ultraviolet radiation (UVR) have consistently reported inverse associations with non-Hodgkin lymphoma (NHL) risk, but prospective studies have yielded mixed results. Few studies have explored these exposures in relation to multiple myeloma (MM) risk. To further evaluate these associations with NHL and MM risk and identify etiologically relevant exposure timing, we pooled data on 566 693 individuals from 6 US prospective cohort studies (11 636 incident NHL; 2749 incident MM; median follow-up: 20 years) and used geographic information systems models to estimate residential ambient UVR levels at time points from birth to adulthood. Using Cox proportional hazards models, we calculated hazard ratios (HRs) and 95% CIs for associations of residential ambie

SUBMITTER: Wang SS 

PROVIDER: S-EPMC12634110 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature