Multimorbidity is significantly associated with higher prevalence of depressive symptoms in middle-aged and older Chinese adults.

ABSTRACT:

Objective

Chronic diseases and depressive symptoms are prevalent global health concerns. This study examined the association between multimorbidity and depressive symptoms in the middle-aged and older adults.

Methods

This cross-sectional study used data from the China Health and Retirement Longitudinal Study (CHARLS, China, 2011-2020), including 18,551 adults aged ≥45 years. Depressive symptoms were assessed with the 10-item Center for Epidemiologic Studies Depression Scale (score ≥10). We analyzed associations for each chronic disease and for their coexistence.

Results

After adjusting for sociodemographic and lifestyle factors, chronic liver disease, cardiovascular disease, chronic kidney disease, and diabetes were significantly associated with depressive symptoms. P

SUBMITTER: Zheng Y 

PROVIDER: S-EPMC12634280 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature