Epidemiological associations between obesity, metabolism and disease risk: are body mass index and waist-hip ratio all you need?

ABSTRACT:

Background/objectives

Tracking excess adiposity at population scale is essential for managing the obesity pandemic in human populations. New formulas based on weight, height, waist and hip measurements have been suggested as better alternatives to the classic body mass index and waist-hip ratio, but the lack of systematic benchmarking on how these formulas reflect adiposity, metabolic dysfunction and clinical sequelae causes confusion on how to best monitor the health of populations.

Subjects/methods

Participants from the Northern Finland Birth Cohort 1966 were included based on data availability at the 46-year visit (2511 women and 1908 men). Cross-sectional sex-adjusted Spearman correlations with clinical biomarkers and serum and urine NMR metabolomics were calculated for

SUBMITTER: Makinen VP 

PROVIDER: S-EPMC12634416 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature