Early life environment moderates association of body composition and internalizing problems in adolescence.

ABSTRACT: Metabolic and depressive disorders are major chronic global health concerns, often co-occurring and mutually reinforcing each other. Thus, understanding risk and protective factors underlying their development is crucial for identifying effective preventive strategies. Participants included N = 10,446 participants (31,418 observations) from the Adolescent Brain Cognitive Development Study aged 10-15 years. Primary outcomes were internalizing problem scores, and random slopes quantifying the within-person coupling between waist-to-height ratio and internalizing problems. Predictors included early-life adversity measures and potentially protective environments measured at the family, community, peer, and school level. Early-life adversity and protective environment scores were examined as mo

SUBMITTER: Buss C 

PROVIDER: S-EPMC12634448 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature