Relationship between trace elements status and atrial fibrillation in patients with valvular heart diseases.

ABSTRACT:

Background

Atrial fibrillation (AF) combined with valvular heart disease (VHD) is increasingly prevalent worldwide and is associated with high morbidity and mortality. Studies have showed trace element concentrations varied in patients with AF and may be involved in the pathogenesis of AF. However, no data is currently available for those with VHD.

Methods

Urine samples as well as clinical data were collected from 72 VHD patients with AF (VHDAF) and 72 VHD patients without AF (VHD) and further analyzed for a panel of trace elements: lithium, manganese, cobalt, copper, zinc, arsenic, selenium, strontium, Cadmium, mercury, thallium, lead. Quantile g-computation was adopted to explore the joint effect of the 12 trace elements on AF in this population, and internal validation wa

SUBMITTER: Liu X 

PROVIDER: S-EPMC12634502 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature