Joint association of indoor allergens, endotoxins, heavy metals, and parabens with allergy-related outcomes in U. S. adults.

ABSTRACT:

Background

While the associations of indoor allergens, endotoxin, heavy metals, and parabens with allergy outcomes are well-studied, the combined association remains unclear. This study examines the association between their combined exposure and allergy outcomes in adults.

Methods

A toatl of 1,065 adults from the National Health and Nutrition Examination Survey (NHANES) 2005-2006 were included in analyses. We applied a weighted logistic regression model to investigate the association between individual exposure to 10 chemicals (including Aspergillus fumigatus, Canf 1, Feld 1, Mus m 1, endotoxin, cadmium, lead, total mercury, methyl paraben, and propyl paraben) and allergy-related outcomes. WQS and BKMR models were further used to examine the combined associations.

SUBMITTER: Xue M 

PROVIDER: S-EPMC12634600 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature