Genomic epidemiological analysis reveals new insights into the resurgence of <i>Mycoplasma pneumoniae</i> in China.

ABSTRACT:

Objectives

After coronavirus disease 2019 pandemic restrictions, Mycoplasma pneumoniae (M. pneumoniae) re-surged widely across the world. This study aimed to determine the genomic epidemiological characteristics of resurging M. pneumoniae, which has dominated the respiratory infection outbreak in Beijing, China, since mid-September 2023.

Methods

M. pneumoniae samples were collected from patients with acute respiratory-tract infections in Beijing in 2018-2023. A total of 160 M. pneumoniae genomes were sequenced via probe-capture-based approach. The genetic features of M. pneumoniae were characterized by multilocus sequence typing and comparative genomic analysis.

Results

In total, 160 patients with M. pneumoniae infectio

SUBMITTER: Wang X 

PROVIDER: S-EPMC12634620 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature