SEER-based hypothesis-generating research for minimum lymph node evaluation in early-stage pancreatic ductal adenocarcinoma patients.

ABSTRACT:

Background

Invasive ductal carcinoma of the pancreas (IDCP) is one of the most lethal of all solid cancers, with regional lymph nodes contributing to recurrent IDCP. Given the dismal prognosis of IDCP, the number of ELNs plays a vital role in patient prognosis. However, the optimal number of examined lymph nodes (ELNs) for stage I and II IDCP patients has not been defined by the 7th and 8th editions of the American Joint Committee on Cancer.

Methods

All patients diagnosed with invasive ductal carcinoma pancreatic cancer were identified from the Surveillance, Epidemiology, and End Results (SEER) database (http://seer.cancer.gov/) using SEER*Stat Software (version 8.3.9.2). The minimum number of ELNs or ELN/regional nodes positive (RNP) ratio threshold for optimal survival of

SUBMITTER: Xu H 

PROVIDER: S-EPMC12634659 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature