Bacteriocin Antagonistic Potentials of Lactococcus cremoris and Lactococcus lactis Isolates from Different Habitats.

ABSTRACT: It has not been extensively examined if the ecological role of lactic acid bacterial bacteriocins may affect their distribution in different habitats and thereby impact screenings for novel variants. Further, the functionality of such variants requires additional investigation. This study investigated the distribution of bacteriocin biosynthetic gene clusters (BGCs) and bacteriocinogenic activity of Lactococcus cremoris and Lactococcus lactis from a range of different environments. Whole genome sequencing and phylogenetic analysis of fifty L. cremoris and L. lactis strains showed distinct species clustering without significant genome size differences between species or sources. Genomic screening with AntiSMASH and BAGEL4 identified several BGCs, with variation based on species but not on h

SUBMITTER: Tang T 

PROVIDER: S-EPMC12634713 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature