The evaluation of artificial intelligence in mammography-based breast cancer screening: Is breast-level analysis enough?

ABSTRACT:

Objectives

To assess whether the diagnostic performance of a commercial artificial intelligence (AI) algorithm for mammography differs between breast-level and lesion-level interpretations and to compare performance to a large population of specialised human readers.

Materials and methods

We retrospectively analysed 1200 mammograms from the NHS breast cancer screening programme using a commercial AI algorithm and assessments from 1258 trained human readers from the Personal Performance in Mammographic Screening (PERFORMS) external quality assurance programme. For breasts containing pathologically confirmed malignancies, a breast and lesion-level analysis was performed. The latter considered the locations of marked regions of interest for AI and humans. The highest score per

SUBMITTER: Taib AG 

PROVIDER: S-EPMC12634717 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature