More than density: validating a mammographic masking prediction model in Dutch breast cancer screening.

ABSTRACT:

Objectives

To validate a lesion masking prediction model, Mammatus, previously developed on a North American cohort, on a larger retrospective breast cancer screening cohort from a single center in the Netherlands.

Materials and methods

Mammatus was applied to all digital mammography screening examinations with a unilateral invasive breast cancer that was either diagnosed at screening or within 24 months after a negative screening, called interval cancers. All mammograms were retrospectively evaluated for the visibility of malignant masses using all available imaging and clinical information. The area under the receiver operator characteristic (ROC) curve (AUC) when using Mammatus to distinguish examinations with screen-detected cancers (assumed low masking risk) from interv

SUBMITTER: Verboom SD 

PROVIDER: S-EPMC12634747 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature