A non-invasive approach to monitoring microcirculatory health before and after hemodialysis in renal patients using nailfold video capillaroscopy with optical reflectance analysis.

ABSTRACT: Maintaining physiological blood pressure is a critical goal in the prevention of cardiovascular events, whereas tissue perfusion depends on the balance between systemic blood pressure and tissue microvascular resistance. The nailfold capillary is considered a window for directly assessing microvascular flow in the body. In this study, nailfold video capillaroscopy was used to determine the acute effects of hemodialysis on microvascular flow dynamics and optical reflectance in 11 patients with renal disease (ages 71 ± 14 years). The study aimed to determine if capillary morphology, flow dynamics, or optical reflectance are sensitive to hemodialysis-induced changes in blood composition. The capillary morphologies, flow speed distributions, and pixel intensity fluctuations before and after he

SUBMITTER: Suzuki H 

PROVIDER: S-EPMC12634960 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature