Clinical Burden and Healthcare Resource Use Among Adults Living with Hemophilia A: An Observational Study.

ABSTRACT:

Introduction

People with hemophilia A (PwHA) may suffer from repeated bleeding in muscles and joints. However, few studies have reported disease burden and healthcare resource utilization (HCRU) in PwHA experiencing bleeding events and/or joint disorders in a real-world setting. The aim of this study was to examine disease burden and HCRU in PwHA via two different categorizations: PwHA with and without medically recorded bleeding (MRB), and PwHA with and without joint disorders.

Methods

This was an observational cross-sectional study of adult male PwHA treated with factor VIII replacement therapy, identified from PharMetrics Plus^® claims data between 2010 and 2019. Comorbidities prevalence and HCRU rates were described. Rate ratios (RRs) of HCRU between PwHA with

SUBMITTER: Young L 

PROVIDER: S-EPMC12635012 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature