Comparative safety of stent retriever designs for intracranial atherosclerotic disease related large vessel occlusion using agarose models.

ABSTRACT: Establishing an optimal first-line approach for suspected intracranial atherosclerotic disease (ICAD)-related acute large vessel occlusion (LVO) remains challenging. We developed an ICAD model using an agarose phantom to investigate the specific features of the stent retriever (SR) design for ICAD-LVO for safety use. An ICAD model that reproduced the mechanical features of plaque was developed to quantify the pull-out resistance and intraluminal injury caused by SRs. The impacts of vessel factors (ICAD existence and plaque stiffness) and SR design (non-segmented, segmented, and manually-controllable-diameter) were evaluated using this model. In the 6% agarose (as soft plaque) ICAD model, SR caused significantly higher pull-out resistance and severe intraluminal injury compared with the non

SUBMITTER: Imaoka Y 

PROVIDER: S-EPMC12635251 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature