Utility of short-term heart rate variability metrics in heart failure with reduced ejection fraction.

ABSTRACT:

Background

Recently, reduced sympathetic nervous system (SNS) activity measured by 10-minute electrocardiogram (ECG)-based heart rate (HR) variability (HRV) was associated with heart failure (HF) with recovered ejection fraction (EF) (HFrecEF). However, there are no studies on the optimal ECG recording time to indicate HFrecEF in short-term HRV.

Objective

In this study, the optimal ECG intervals and time-domain metrics to elucidate indicators for HFrecEF were investigated in HF with reduced EF (HFrEF).

Methods

HRV analyses based on 2-, 4.5-, and 9-minute ECG intervals were performed in 4 groups: patients with persistent HFrEF (n = 40), HFrecEF (n = 41), and stage A HF (n = 73) and healthy controls (n = 40).

Results

Mean HR and triangular and SNS indexes were si

SUBMITTER: Nagai M 

PROVIDER: S-EPMC12635738 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature