Efficacy and safety of left bundle branch pacing compared with left ventricular septal pacing: A systematic review and meta-analysis.

ABSTRACT:

Background

Although numerous studies have compared the efficacy and safety of left bundle branch pacing (LBBP) and left ventricular (LV) septal pacing (LVSP), the results remain inconclusive.

Objective

This meta-analysis aimed to systematically compare the efficacy and safety of LBBP with that of LVSP.

Methods

A comprehensive literature search was conducted across PubMed, Europe PMC, and ScienceDirect to identify studies comparing procedural duration, complications, electrophysiological and echocardiographic parameters, and clinical outcomes between LBBP and LVSP.

Results

A total of 22 cohort studies, involving 1360 LBBP and 1186 LVSP procedures, were included. The paced QRS duration (mean difference [MD] = -9.65 ms; 95% confidence interval [CI], -13.35 to -5.9

SUBMITTER: Putra ICS 

PROVIDER: S-EPMC12635747 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature