Screening Natriuretic Peptide Levels Predicts Heart Failure and Death in Individuals With Type 1 and Type 2 Diabetes Without Known Heart Failure.

ABSTRACT:

Objective

Heart failure (HF) is common in diabetes and may be asymptomatic in early stages. N-terminal pro-brain natriuretic peptide (NT-proBNP) and B-type natriuretic peptide (BNP) (collectively natriuretic peptides [NPs]) are markers that can be used to detect early HF in asymptomatic individuals who may benefit from disease-modifying therapies. We examined the prognostic role of NP levels in people with type 1 diabetes (T1D) or type 2 diabetes (T2D) without known HF.

Research design and methods

Optum's de-identified Market Clarity Data were queried for adults (aged ≥18 years) with T1D or T2D without known HF who received an outpatient NP test between 2017 and 2023. Associations between NP levels and incident HF or death were assessed using multivariable Cox proportional h

SUBMITTER: Pop-Busui R 

PROVIDER: S-EPMC12635886 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature