Microbial Feast or Famine: dietary carbohydrate composition and gut microbiota metabolic function.

ABSTRACT: Diet composition plays a major role in shaping the structure and function of the gut microbiota and influencing host health. While numerous studies have investigated the impact of macronutrient type and quantity on microbiota using in vitro systems, animal models, and human participants, most of these studies focused primarily on microbial-community composition and lacked the functional information that can be gained from transcript-level analyses. In this exploratory analysis, we use metatranscriptomic data to gain a functional perspective on how dietary composition is associated with the gut microbiota and hypothesized implications for host physiology. Data were derived from a tightly controlled, randomized cross-over feeding study conducted in a metabolic ward, where participants

SUBMITTER: Dirks B 

PROVIDER: S-EPMC12636310 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature