Public Omics Explorer (POE): Enabling integrative semantic search across GEO omics datasets based on PubMed publications.

ABSTRACT: The exponential growth of publicly available omics datasets and biomedical literature has created both opportunities and challenges for data-driven discovery in life sciences. While the Gene Expression Omnibus (GEO) hosts millions of high-throughput experimental datasets, the European Nucleotide Archive (ENA) stores the corresponding raw sequencing data, and PubMed contains an extensive body of related scientific publications, integrated exploration of these resources remains limited. We present Public Omics Explorer (POE), a web-based platform that performs literature‑informed dataset retrieval, semantically linking GEO datasets and ENA records through their associated PubMed publications. POE automatically collects and indexes GEO metadata, ENA cross‑references, and PubMed abstracts on a

SUBMITTER: Grigoriadis D 

PROVIDER: S-EPMC12636342 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature