A trait syndrome ties cell morphology to glycolysis across the yeast subphylum.

ABSTRACT: Traits that co-vary across species can provide fundamental insights into the trade-offs and constraints that govern their evolution. In a recent article in Current Biology, Li et al.¹ reported that glucose uptake rates (GUR) are inversely correlated with the cell surface area-to-volume (SA:V) ratio across 11 yeast species. Here we substantially expand this analysis to 282 species to test whether the GUR-SA:V correlation generalizes across the ancient Saccharomycotina yeast subphylum and to determine the contribution of shared evolutionary history to the co-variation of these two traits. Using regression models that account for co-variation due to phylogeny, we found that extracellular acidification rates (ECAR, which we used as a proxy for GUR) had a significant correlati

SUBMITTER: Horianopoulos LC 

PROVIDER: S-EPMC12636413 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature