Synaptotagmin-1 regulates egg production by con trolling luteinizing hormone secretion in chickens.

ABSTRACT: Egg production represents one of the most economically critical traits in commercial poultry production, orchestrated primarily by the hypothalamus-pituitary-ovarian (HPO) axis. Synaptotagmin 1 (SYT1), a ubiquitous component of the nervous and endocrine systems, functions as a key mediator of calcium-dependent neurotransmitter release and hormone secretion. However, the functional role of SYT1 in avian reproductive performance has remained elusive. In this study, we present evidence that single nucleotide polymorphisms (SNPs) within the SYT1 gene effectively distinguish commercial laying hens from local wild breeds, as demonstrated through principal component analysis (PCA), suggesting the gene's pivotal role in selective breeding for enhanced egg production. Through genotype-phenotype cor

SUBMITTER: Cheng Z 

PROVIDER: S-EPMC12637056 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature