Association Between New-Onset Proteinuria During Hospitalization and Cardiovascular Mortality Among Patients With Atherosclerotic Cardiovascular Disease.

ABSTRACT:

Background

Evidence regarding the prognostic value of new-onset proteinuria during hospitalization among patients with atherosclerotic cardiovascular disease (ASCVD) is lacking.

Objectives

We aimed to examine the associations of new-onset proteinuria during hospitalization with cardiovascular (CV) mortality and composite kidney outcomes after discharge.

Methods

This observational cohort study included hospitalized adults with ASCVD and without proteinuria at admission from twenty-four academic hospitals participated in China Renal Data System. New-onset proteinuria during hospitalization was defined as a change in urinary protein test from negative to 1+ or more. The primary outcome was CV mortality after discharge. The secondary outcome was the composite of adverse k

SUBMITTER: Su L 

PROVIDER: S-EPMC12637060 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature