Incidence and characteristics of Guillain-Barre syndrome in Taiwan before and during the COVID-19 pandemic: A 12-year single-center experience.

ABSTRACT:

Background

There is substantial regional disparity in the presentation of Guillain-Barré syndrome (GBS), and coronavirus disease 2019 (COVID-19) possibly influences the development of GBS, but the association remains uncertain. This study aimed to investigate the incidence of GBS before and during the COVID-19 pandemic and delineate the clinical profile of GBS in Taiwanese patients.

Methods

Medical records of 185 ascertained GBS cases at Taipei Veterans General Hospital between 2011 and 2022 were reviewed. Patients were analyzed based on age, clinical subtypes, and electrophysiological findings. A multivariable ordinal logistic regression was conducted to identify factors related to outcomes measured by the GBS disability scale (GBS-DS), which ranges from 0 to 6, with higher

SUBMITTER: Chen YH 

PROVIDER: S-EPMC12637126 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature