Prolonged Prophylactic Ureteral Stent Placement and BK Polyomavirus Infection After Renal Transplantation-A Retrospective Case-control Study.

ABSTRACT:

Background and objective

BK polyomavirus (BKPyV) poses a significant challenge in kidney transplant (KTX) recipients, potentially leading to BKPyV-associated nephropathy. Prophylactic ureteral stent (UrSt) placement is the standard care following KTX. Emerging data suggest that UrSt may influence the incidence and severity of BKPyV-DNAemia. We hypothesized a dose-dependent relationship between an indwelling UrSt and the risk of BKPyV-DNAemia in KTX recipients.

Methods

We included all KTX recipients with detectable BKPyV-DNAemia at the Medical University of Vienna from 2010 to 2021; those without DNAemia served as controls. This nested, retrospective, 1:1 sex- and age-matched case-control study assessed whether UrSt placement and/or its duration was associated with BKPyV.

SUBMITTER: Omic H 

PROVIDER: S-EPMC12637267 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature