An Accessible Python Framework for Real-Time Magnetic Tweezers Microscope Control and Image Processing.

ABSTRACT: Magnetic tweezers are a popular biophysical instrument for manipulating and measuring single molecules. Most groups rely on custom-built setups tailored to specific experiments, making it challenging to implement and share software. Typically, image acquisition and hardware control are automated via LabVIEW, while real-time video processing is implemented in C++/CUDA libraries. Live processing can eliminate the need to store raw video, enabling high throughput, fast acquisition rates, and simplified experimental workflows. However, no open-source general-purpose software framework currently unifies these capabilities for magnetic tweezers experiments. Here, we introduce MagTrack and MagScope open-source Python-based tools designed to fill this gap. MagTrack is an image-processing library t

SUBMITTER: London JA 

PROVIDER: S-EPMC12637577 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature