Impact of Collateral Circulation on Poststroke Epilepsy After Mechanical Thrombectomy for Large Vessel Occlusive Stroke: A Multicenter Cohort Study.

ABSTRACT:

Background

Acute ischemic stroke (AIS) represents a significant etiology of acquired epilepsy in adults. However, there remains a paucity of evidence concerning predictive factors for poststroke epilepsy (PSE) among patients undergoing mechanical thrombectomy (MT). We aimed to evaluate the association between poor collateral circulation and the risk of PSE.

Methods

This multicenter cohort study included AIS patients who underwent MT (2017-2022) at three tertiary centers. Adjusted Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for PSE risk. Subgroup analyses, sensitivity analyses, and competing risk analyses were also performed.

Results

We included 1167 patients (mean age: 62 years; 46.5% female). PSE frequen

SUBMITTER: Jiang P 

PROVIDER: S-EPMC12637856 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature