Construct Validity of the Toronto IBD Global Endoscopic Reporting Score Compared to Inflammatory Biomarkers After 12-Month Follow-Up.

ABSTRACT:

Background and aims

The Toronto IBD Global Endoscopic Reporting (TIGER) score is a single endoscopic scoring index for both patients with Crohn's disease (CD) and ulcerative colitis (UC). The goal of this study was to assess the direct relationship between TIGER scores and fecal calprotectin (FC) and C-reactive protein (CRP) after 12 months.

Methods

A prospective 12-month study conducted in 1 tertiary IBD center. Baseline colonoscopy was performed. Moderate-to-severe mucosal involvement was defined as a TIGER score ≥ 100, Simple Endoscopic Score for Crohn's disease ≥ 6, Mayo Endoscopic Score > 1. FC and CRP levels were documented at each visit. Baseline TIGER, SES-CD, and MES were utilized as a predictor for FC and CRP levels after 12 months.

Results

The study populat

SUBMITTER: Zittan E 

PROVIDER: S-EPMC12638056 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature