Food Compounds Associated With Disease Activity in Inflammatory Bowel Disease.

ABSTRACT:

Background

Diet plays a modulatory role in inflammatory bowel disease (IBD), but specific relevant dietary factors have yet to be identified. To advance our understanding, we performed multivariate analyses of food compound intakes using dietary data from an IBD cohort.

Methods

We used dietary and disease status data from IBD patients at the University Medical Center Utrecht, The Netherlands. Intake levels for 768 compounds from 135 patients were calculated. Using random forest analyses, we explored associations between compound intake and IBD activity by comparing patients who experienced flares (n = 41) with those who remained in remission during follow-up. We assessed the potential biological relevance of the most significant compounds (n = 35) by examining literature on

SUBMITTER: Meima M 

PROVIDER: S-EPMC12638057 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature