Impact of Dronedarone on Early Recurrence After Catheter Ablation in Patients With Nonparoxysmal Atrial Fibrillation.

ABSTRACT:

Objective

This study is aimed at comparing the efficacy and safety of dronedarone, amiodarone, and propafenone in preventing early recurrence of atrial arrhythmias during the blanking period following catheter ablation in patients with nonparoxysmal atrial fibrillation.

Methods

We retrospectively analyzed 408 patients with nonparoxysmal atrial fibrillation who underwent their first catheter ablation. Patients were divided into three groups based on the postoperative antiarrhythmic drug prescribed: dronedarone, amiodarone, or propafenone. A propensity score matching (PSM) analysis was performed as the primary analysis to compare early recurrence rates and drug-related adverse events. An inverse probability of treatment weighting (IPW) analysis was conducted as a sensitivity a

SUBMITTER: Long X 

PROVIDER: S-EPMC12638134 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature