The Endoscopic Versus Open Approach for Anterior Skull Base Tumors: A Systematic Review of Comparative Outcomes and a Framework for Surgical Selection.

ABSTRACT:

Background

Anterior skull base tumors (ASBTs) pose significant surgical challenges due to their proximity to critical neurovascular structures. Surgical management has evolved with the adoption of both endoscopic and open approaches. This systematic review synthesizes evidence comparing these approaches in terms of complications, outcomes, and indications.

Methods

We conducted a systematic review following the PRISMA guidelines, analyzing studies published between 1981 and 2022. A total of 1200 articles were initially identified from databases including PubMed, MEDLINE, JSTOR, and ScienceDirect, with 60 relevant references ultimately included. Data extraction focused on surgical approaches, tumor types, prevalence, and complications.

Results

ASBTs exhibit varying prev

SUBMITTER: Mian UU 

PROVIDER: S-EPMC12638158 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature