Oncological Outcome for 83 Consecutive Patients With Malignant Peripheral Nerve Sheath Tumors Treated at a Tertiary Referral Centre.

ABSTRACT:

Background

Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft tissue sarcomas with a high risk of recurrence and a poor prognosis, and there is a lack of knowledge regarding long-term follow-up and response to oncological treatment.

Aims

The aim of this study was to investigate what treatment the patients received and to examine the outcome for patients with MPNST.

Methods and results

This is a retrospective study of patients treated for MPNST at Karolinska University Hospital between 2003 and 2022. Data regarding surgical and oncological treatment and follow-up were collected. Eighty-three patients were identified and included in the study. Tumor grade is available for 72 patients, of which 64 had high-grade tumors. Seventy-nine patients were primarily o

SUBMITTER: Yeomans HVM 

PROVIDER: S-EPMC12638222 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature