Racial and ethnic disparities and socioeconomic determinants of male breast cancer mortality in the United States.

ABSTRACT:

Purpose

Male breast cancer (mBC) is rare and accounts for ~ 1% of all breast cancer cases in the United States (US), and mBC incidence has risen in recent years. This study sought to examine mBC mortality disparities across racial/ethnic groups and associated socioeconomic determinants at the national level.

Methods

This retrospective study analyzed the 2010-2021 National Cancer Database. Patients were eligible if they were ≥ 18 years, were male sex, and had stage I-IV disease, with available data on receptor status. Overall survival (OS) was modeled using Cox regression adjusting for demographic, socioeconomic, and clinicopathologic factors.

Results

Of 20,470 mBC (mean age, 66.2 [SD, 12.6] years), 2.5% were Asian or Pacific Islander, 13.8% Black, 4.0% Hispanic, and 7

SUBMITTER: Freeman JQ 

PROVIDER: S-EPMC12638332 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature