Predictive Performance of Raman Spectroscopy in Osteoarthritis: A Systematic Review.

ABSTRACT: Early diagnosis of osteoarthritis (OA) remains a critical unmet need due to the lack of reliable detection methods. Detecting OA at an early stage provides a valuable clinical window for implementing effective intervention strategies. Raman spectroscopy (RS) holds promise for improving predictive accuracy in detecting osteoarthritic changes at the molecular level, monitoring disease progression, and assessing severity. This study aimed to systematically evaluate the predictive performance of RS in OA assessment in human samples, thereby highlighting current advancements in the field. The search included PubMed/Medline, Scopus, Web of Science, and IEEE for studies published up to July 31, 2024. Two authors individually screened the studies using Covidence software, and data extraction was b

SUBMITTER: Yesmean M 

PROVIDER: S-EPMC12638382 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature