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ABSTRACT: Background
Brachial artery endothelial function, measured by the flow-mediated dilatation (FMD) technique, serves as a surrogate for coronary endothelial function and is recognized as an independent predictor of cardiovascular disease risk. Despite the known benefits of physical exercise interventions (PEI) in improving endothelial function, limited evidence exists to guide practitioners on the most effective form of PEI for enhancing endothelial function. The aim of this article is to investigate the effects of different PEI modalities on brachial artery FMD, and to establish the most effective PEI through a systematic review and network meta-analysis (NMA).Methods
PubMed, WoS, CINAHL, EMBASE, CENTRAL and EBSCOhost search was conducted from inception to February 20th, 2025
SUBMITTER: Paravlic AH
PROVIDER: S-EPMC12638609 | biostudies-literature | 2025 Nov
REPOSITORIES: biostudies-literature