Genomic monitoring and tracking of mpox virus clade Ib in Burundi between july to september 2024.

ABSTRACT:

Background

Since the first identification of mpox virus (MPXV) clade Ib in Burundi in July 2024, Burundi is one of the most affected countries in this evolving outbreak outside of the DRC.

Methods

Here we aimed to understand the route(s) of introduction and spread of MPXV throughout the first months of the outbreak in Burundi. In total, 98 genome sequences from cases diagnosed during the first three months of the outbreak were generated.

Results

Here we show using phylogenetic analysis that the virus was introduced from the DRC and Bayesian evolutionary analysis shows that different clusters could be identified in Burundi leading to further spread within the country.

Conclusions

In summary, we identify sustained circulation of clade Ib MPXV in Burundi, most lik

SUBMITTER: Nzoyikorera N 

PROVIDER: S-EPMC12639094 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature