Development and validation of a nomogram for predicting the risk of malignancy in intraductal papillary neoplasms: a retrospective study.

ABSTRACT:

Objective

Development and validation of a simple, accurate nomogram for predicting the risk of malignancy in intraductal papillary neoplasms (IPNs).

Background

Some studies have explored the independent risk factors associated with malignant IPNs, but no validated predictive model has been developed to help clinicians assess the probability of malignancy in patients with IPNS.

Methods

This case-control study included 6646 patients with IPNs which date came from single-center. A nomogram predicting the malignant probability of IPNs was developed by incorporating independent predictors identified through multivariate logistic regression analysis, and the nomogram was externally validated.

Results

Age ≥50 years, bloody discharge, palpable tumor, postmenopausal sta

SUBMITTER: Pang H 

PROVIDER: S-EPMC12639384 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature