Refining Active Surveillance Eligibility in Intermediate-risk Non-muscle-invasive Bladder Cancer: The Impact of Time to First Recurrence.

ABSTRACT: The International Bladder Cancer Group (IBCG) scoring system has been proposed for identifying patients suitable for active surveillance (AS) within the intermediate-risk (IR) non-muscle-invasive bladder cancer (NMIBC) population. Given that early recurrence has been associated with higher progression rates, we aimed to assess whether better integration of recurrence-free survival (RFS) into the IBCG risk stratification may further improve AS eligibility criteria. We retrospectively identified 241 recurrent IR-NMIBC patients (during the period 2013-2022) who were eligible for AS at the time of the first transurethral resection of a bladder tumor. Kaplan-Meier and multivariable Cox regression analyses evaluated the impact of IBCG risk factors and recurrence timing in predicting high-grade (

SUBMITTER: Finati M 

PROVIDER: S-EPMC12639428 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature