Cellular pH homeostasis shapes root system architecture by modulating auxin-mediated developmental responses.

ABSTRACT: Cell expansion relies on turgor pressure and acidification-dependent loosening of the rigid cell wall. Distinct cell surface-based and intracellular auxin signaling pathways synergistically activate plasma membrane H+-ATPases, acidifying the apoplast, a prerequisite for cell elongation. Unlike in shoots, auxin inhibits cell elongation in roots. This auxin paradox highlights a largely unknown antagonistic pathway, driving root apoplast alkalinization. Auxin fluxes, regulated by the TINY ROOT HAIR 1 (TRH1)/POTASSIUM (K+) UPTAKE 4 (KUP4) transporter, modulate root gravitropism and root hair morphogenesis through the acropetal and basipetal auxin transport pathways, respectively. Here, we show that under acidic conditions, wild-type Arabidopsis (Arabidopsis thaliana) seedlings develop shorter

SUBMITTER: Templalexis D 

PROVIDER: S-EPMC12639547 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature