Integrated risks from air pollution and climate extremes: synergistic effects of ozone, heat, and humidity on cardiovascular mortality.

ABSTRACT:

Background

Climate change has significantly increased adverse effects on cardiovascular disease (CVD). Ozone (O₃) exposure is recognized as a risk factor for CVD mortality. However, few studies have analyzed the modifying effects of climatic factors on O₃, particularly in subtropical regions. This study analyzed the association between O₃ and CVD mortality in Zhejiang Province, China, while evaluating the modifying effects of temperature and humidity.

Methods

Using mortality, air pollution, and meteorological data from 11 cities (2019-2023) in Zhejiang Province, China, we employed distributed lag nonlinear models (DLNMs) to assess lagged and cumulative O₃ effects. For effect modification, a general linear model (GLM) was used to qu

SUBMITTER: Wei Q 

PROVIDER: S-EPMC12639647 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature