Exploring social determinants of health in the context of metabolic and circadian influences on new hip fracture risk: longitudinal insights from CHARLS.

ABSTRACT:

Background

The risk of hip fractures is closely intertwined with social determinants of health (SDHs), metabolic factors, and circadian rhythm-related variables. Understanding the combined effects of these factors, particularly in the elderly population of China, has substantial public health implications.

Methods

This study utilized data from the China Health and Retirement Longitudinal Study (CHARLS, 2011-2020), which included 11,928 individuals aged 45 years and older, all free from a history of hip fractures. Kaplan-Meier survival curves, multivariable Cox proportional hazards models, and restricted cubic spline (RCS) analysis were applied to explore the associations between SDHs and hip fracture risk, stratified by metabolic syndrome (MetS) and circadian rhythm syndrome

SUBMITTER: Hu P 

PROVIDER: S-EPMC12639743 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature