Diabetes modifies the association between the triglyceride-glucose index and subclinical myocardial injury: A prospective cohort study.

ABSTRACT:

Background

Triglyceride-glucose (TyG) index is considered an alternative indicator of insulin resistance and is associated with cardiovascular diseases. However, its association with subclinical myocardial injury in a general population without known cardiovascular disease has not been investigated, nor has the effect of diabetes.

Methods

Individuals without known cardiovascular disease were included from the Atherosclerosis Risk in Communities (ARIC) cohort. The baseline TyG index was calculated as ln [fasting triglycerides (mg/dL) × fasting glucose (mg/dL)/2]. The association between the baseline TyG index and subclinical myocardial injury [high-sensitivity cardiac troponin T (hs-cTnT≥ 14 ng/L)] was assessed using both cross-sectional and prospective cohort designs.

Res

SUBMITTER: Abudukeremu A 

PROVIDER: S-EPMC12639786 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature