Shiga Toxin-Producing <i>Escherichia coli-</i>Associated Hemolytic Uremic Syndrome in Adult Kidney Transplant Recipients.

ABSTRACT:

Introduction

Shiga toxin (Stx)-producing Escherichia coli (E coli)-associated hemolytic uremic syndrome (STEC-HUS) is an acquired form of thrombotic microangiopathy (TMA) caused by food and waterborne infection. It remains the leading cause of acute renal injury (AKI) in children. In adults, STEC-HUS is less common but often more severe. Data on STEC-HUS in kidney transplant recipients (KTRs) are limited.

Methods

We conducted a retrospective study involving adult KTRs diagnosed with STEC-HUS between January 2012 and April 2022 across 15 French nephrology centers. We aimed to characterize the clinical, biological, and microbiological features of STEC-HUS in this population, its management, and outcomes.

Results

A total of 35 adult KTRs were included. The annual

SUBMITTER: Mazloum M 

PROVIDER: S-EPMC12639813 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature